On the other hand, no activating mutation of c-kit was found in breast cancer (Simon et al, 2004) and c-kit is physiologically expressed in the normal gland of the breast (Natali et al, 1992a; Tsuura et al, 2002; Ulivi et al, 2004; Yared et al, 2004). The gene discussed is KIT; the disease is breast carcinoma.