When the CAM assay was performed using ACN/IFN-γ or ACN/neo tumour xenografts, the number of vessels macroscopically counted around the implant was significantly lower in ACN/IFN-γ than in ACN/neo biopsies (15±3 vs 34±4, P<0.001, as shown in Figure 5C and E, respectively). This evidence concerns the gene IFNG and neoplasm.