IFNA1 and neoplasm: In this view, it is conceivable that a non-species-specific mediator, like NO, was responsible for inhibition of angiogenesis observed in other human IFN-transfected tumour cells growing in athymic mice (Hock et al, 1993; Fathallah-Shaykh et al, 2000; Ozawa et al, 2001; Izawa et al, 2002; Qin et al, 2002).