CALCA and bacterial infectious disease with sepsis: Enguix et al. [20] evaluated serum PCT as a diagnostic marker of bacterial sepsis in newborns aged 3–30 days admitted to the NICU (20 neonates with sepsis, 26 neonates without sepsis), and found a sensitivity of 98.6% and specificity of 88.9% for an optimum diagnostic cutoff value of ≥ 8.05 ng/mL, without statistically significant differences in comparison with CRP and serum amyloid.