BCL11A and B-cell chronic lymphocytic leukemia: Previously we identified a Krüppel zinc finger-encoding gene, B-cell lymphoma/leukemia 11A (BCL11A) and showed it to be disrupted and deregulated in four aggressive cases of B-cell chronic lymphocytic leukemia (B-CLL) with t(2;14)(p16.1;q32.3) that lacked mutations within their expressed variable (VH) region genes [3-5].