VEGFA and neoplasm: There is substantial crosstalk between angiogenesis and lymphangiogenesis in tumour progression as evidenced by the involvement of lymphangiogenic factors VEGF-C, D and their receptor VEGFR3 in angiogenesis and the role played by angiogenic factors VEGF-A and Angiopoetin 2 in lymphangiogenesis respectively (Scavelli et al, 2004).