Firstly, that an elevated C-reactive protein identifies those patients with an impaired T-lymphocytic response, as poor infiltration of GI tumours appears to be associated with poor outcome (Schumacher et al, 2001; Ali et al, 2004) and an elevated C-reactive protein concentration has recently been shown to be inversely associated with T-lymphocyte subset infiltration (Canna et al, 2005). Here, CRP is linked to digestive system neoplasm.