CYP19A1 and breast cancer: Employing these techniques using data from the Multiethnic Cohort (MEC) Study recruiting African-American, Hawaiian, Japanese, Latina and white women, Haiman et al [12] utilized twenty-five haplotype-tagging SNPs (htSNPs) to predict the common haplotypes with high probability within the CYP19 gene and genotyped these htSNPs in a breast cancer case-control study nested in the MEC Study (cases, n = 1355; controls, n = 2580).