ANXA5 and systemic lupus erythematosus: SLE patients exhibited higher levels of apoptotic cells in the total PBMC population at 24 hours, as measured by annexin-V staining (median [interquartile range]: 3.25% [2.25–5.15%] versus 2.20% [1.7–3.35%], P = 0.012; Figure 1a).