VEGFC and metastatic malignant neoplasm in the lymph nodes: Clinicopathological studies carried out over the past 7 years have reported that expression of VEGF-C, VEGF-D or VEGFR-3 can correlate with lymph node metastasis in human cancer, a topic that has been extensively reviewed in recent times (Stacker et al, 2002a, 2002b; He et al, 2004).