Of the 4 different disease loci for which we have obtained coverage with ≥4 ESTs - spinocerebellar ataxia 6 (CACNA1A or SCA6), dentarubro-pallidolusyan atrophy, Huntington's disease and spinocerebellar ataxia 7 (SCA7) - we detected repeat size polymorphic variants for the first two. Here, CACNA1A is linked to juvenile Huntington disease.