A strong candidate factor involved in such tissue-specific functions is EGFR, since we observed in clinical specimens the correlation of gene expression between FABP7 and EGFR, and the correlation of nuclear FABP7 immunoreactivity with EGFR expression; however, this association appears to be only in GBM, but not in normal brain, gliotic tissues, or other types of glioma examined. The gene discussed is EGFR; the disease is glioma.