A strong candidate factor involved in such tissue-specific functions is EGFR, since we observed in clinical specimens the correlation of gene expression between FABP7 and EGFR, and the correlation of nuclear FABP7 immunoreactivity with EGFR expression; however, this association appears to be only in GBM, but not in normal brain, gliotic tissues, or other types of glioma examined. This evidence concerns the gene FABP7 and central nervous system cancer.