Because pilocytic astrocytomas are well-demarcated lesions whose pattern of growth is clearly distinctive from diffusely infiltrative higher-grade (grades II to IV) astrocytoma and oligodendroglial tumors (both ODG and OAC), considering the association of nuclear FABP7 with poor prognosis of GBM patients, cytoplasmic localization of FABP7 may be associated with less infiltrative phenotype of neoplastic astrocytes. The gene discussed is FABP7; the disease is glioblastoma.