After adjustment for other significant risk factors predisposing to AF (presence of electrocardiographic LVH, ischemic heart disease, hypertension, renal dysfunction, elevated CRP, and micro- or macroalbuminuria), the association between CETP TaqIB polymorphism and AF remained significant (Odds ratio [95% confidence intervals] for AF: 0.35 [0.16–0.76], p = 0.008). This evidence concerns the gene CRP and Abnormal renal physiology.