BCL2 and B-cell non-Hodgkin lymphoma: A recent study suggests that strong expression of Bcl-2 in the subset of PCFCL with a diffuse large cell histology and primary cutaneous large B-cell lymphoma, other, is associated with a more unfavourable prognosis.2 However, it is important to exclude systemic B-cell lymphoma when Bcl-2 expression is found in PCFCL (Figure 1).