A few cases have been reported to express CD5, some are known to be CD43+, although the frequency of the latter is probably lower than in gastric MALT lymphomas.90 Nuclear Bcl-10 expression has been demonstrated to be strong in t(1;14)(q22;q32)+ cases and moderate in almost all t(11;18)(q21;q21)+ MALT lymphomas.83 In daily practice, however, the immunohistochemical detection of Bcl-10 expression cannot be recommended as a reliable tool for the demonstration of the t(11;18)(q21;q21). This evidence concerns the gene SPN and MALT lymphoma.