Adhesion of pancreatic cancer cell lines to vitronectin yielded the most wide-ranging results, with MiaPaCa-2, Capan-1, AsPC-1, and Panc-1 exhibiting strong adhesion and proliferation (MiaPaCa-2 and AsPC-1), and CFPAC, FG, Colo-357, and BxPC-3 exhibiting weak adhesion and proliferation (CFPAC, FG, and BxPC-3). Here, VTN is linked to familial pancreatic carcinoma.