In patients with BD, we detected a significant positive correlation between serum IgM specific to Sip1 C-ter and soluble E-selectin serum levels (r = 0.36, P = 0.023; Figure 3), whereas we found no significant correlation between anti-Sip1 IgG and IgA and soluble E-selectin. The gene discussed is CD40LG; the disease is Behcet disease.