It was previously demonstrated that the length of an initial response to platinum-based chemotherapy in ovarian cancer is predictive of the duration of future responses[58] After completing accrual to the phase II portion of the current trial, we will determine whether this schedule of GM-CSF and IFN-γ1b plus carboplatin enhances progression-free survival over prior courses of treatment. The gene discussed is CSF2; the disease is ovarian carcinoma.