An association between COX-2 and VEGF-C, either at the mRNA or protein levels, has also been reported for squamous cell carcinomas of the head and neck (Kyzas et al, 2005), oesophagus (Byeon et al, 2004; von Rahden et al, 2005), and non-small cell lung cancer (Su et al, 2004). Here, VEGFC is linked to non-small cell lung carcinoma.