APOE and type 1 diabetes mellitus: Apo E release was measured by ELISA in LPS-activated monocytes and was 3,017 ng/ml (range 2,800–3,100) from controls and 2,961 ng/ml (range 2,957–3,200) from T1D monocytes and therefore was similar in LPS-activated monocytes from controls and T1D patients (Figure 2D).