IFNG and systemic lupus erythematosus: Peripheral blood T cells from active SLE patients spontaneously produced significantly larger amounts of IFN-γ than did those from patients with inactive SLE and normal control individuals (median values: active SLE, 0.85 pg/ml; inactive SLE, <0.63 pg/ml [P < 0.05]; normal controls, <0.63 pg/ml [P < 0.05]; Figure 4a).