Finally, a comparative genomic hybridization (CGH) analysis of 43 grade III invasive ductal breast carcinomas positive for basal cytokeratin 14, and 43 grade- and age-matched CK14-negative controls found significant differences in CGH profiles between these two groups in terms of mean number of changes and types of chromosomal alterations [33]. The gene discussed is KRT14; the disease is invasive ductal breast carcinoma.