TFF1 and colon mucinous adenocarcinoma: Several mucin-related molecules involved in carbohydrate metabolism and protein glycosylation were identified including FUT3, GCNT3, SI, FBP1, UGT1A9; and TFF1, an estrogen-regulated member of the trefoil factor family of secreted peptides associated with mucin production and frequently overexpressed in other mucinous adenocarcinomas (Emami et al, 2004).