Several putative oncogenes were differentially expressed in MOC, including the breast tumour kinase BRK (PTK6) (Barker et al, 1997) not previously implicated in ovarian cancer pathogenesis; and MST1R/RON, a receptor tyrosine kinase associated with proliferation and motility of cancer cells including ovarian carcinoma (Hess et al, 2003; Maggiora et al, 2003; Wang et al, 2003). The gene discussed is PTK6; the disease is ovarian carcinoma.