MIP-1α, GRO-α and MCP-1 levels were significantly higher in patients with septic shock than those in patients with sepsis (P = 0.009, P = 0.005 and P = 0.006, respectively), whereas there was no significant difference in IL-8 levels between patients with sepsis and septic shock (P = 0.066). This evidence concerns the gene CXCL8 and Sepsis.