Upregulation in cancers was seen in TWISTNB 4, YPEL2 3, CBX3 3, SOX9 8 and β-catenin 7, while downregulation was seen in TWISTNB 6, YPEL2 1, YPEL5 3, SEPT4 2, SEPT6 4, CBX3 3, SOX9 2 and β-catenin 2, compared with those in normal mucosa. This evidence concerns the gene SEPTIN6 and cancer.