GPT and metabolic dysfunction-associated steatohepatitis: Different studies have shown that an age of 45 years or more, the extent of obesity, type 2 diabetes, high levels of alanine aminotransferase and triglycerides, high HOMA indices of insulin resistance, systemic hypertension, and high level of C-peptide [6,15,16] are associated with advanced fibrosis in patients with NASH.