Activation of PPARγ has been showed to inhibit proliferation and induce apoptosis in a variety of malignant tumours (Kubota et al, 1998; Mueller et al, 1998; Kitamura et al, 1999; Motomura et al, 2000; Tsubouchi et al, 2000; Ohta et al, 2001; Yang and Frucht, 2001). The gene discussed is PPARG; the disease is cancer.