CDH1 and breast cancer: As determined by one-way ANOVA, the normalised starting quantity, a measure for the amount of mRNA in the sample, differed significantly between tumour cell lines with CDH1 promoter methylation with a fibroblastic morphology (‘Fibroblastic-Tumour’ cluster) and epithelial breast cancer cell lines (‘Epithelial-Ecad-Expressing’ and ‘Epithelial-CDH1-Mutated’ clusters) for several genes (Table 4).