All the testicular seminomas and ovarian dysgerminomas tested (cases 1–13), as well as seminoma components in testicular mixed germ cell tumours (cases 14 and 15), showed strong (+++) granular cytoplasmic staining with anti-dbpC antibody, whereas they were negative for dbpA (Figure 3). The gene discussed is YBX2; the disease is dysgerminoma of ovary.