In fact, immunohistochemical analysis has shown that CT antigens such as MAGE-1, MAGE-3, NY-ESO-1, and CT7 are frequently found in only a small proportion of cancer tissues (Jungbluth et al, 2000, 2002), an indication that the cancers contain both stem cells and differentiated cells (Simpson et al, 2005). The gene discussed is MAGEA3; the disease is cancer.