FRAT1 and ovarian adenocarcinoma: By using in situ hybridisation to detect the expression of FRAT1 and by using immunohistochemistry to detect the expression of β-catenin on tissue microarrays of paraffin-embedded ovarian adenocarcinomas, we report here that cytoplasmic/nuclear accumulation of β-catenin is closely associated with FRAT1 overexpression in ovarian serous adenocarcinomas.