Data on several prognostic factors have recently accumulated, including the hormone receptor status, Her-2 expression, lymph node metastasis and tumour size (Suo et al, 2002; Guerra et al, 2003; Cianfrocca and Goldstein, 2004), and overexpression of cyclins and Her-2 has been reported to enhance metastatic potential (Kuhling et al, 2003; Regitnig et al, 2004). Here, ERBB2 is linked to neoplasm.