FII G20210A mutation is less frequent than factor V Leiden, but it is found in 17% of pregnant patients with thromboembolism.5 In a series of 84 pregnancies in 47 women with combined thrombophilia (factor V Leiden and FII G20210A mutations), the relative risk of pregnancy-related VTE was 2.9, in comparison with women carrying only the FII G20210A mutation. Here, F5 is linked to Rare hereditary thrombophilia.