PGF and psoriasis: Four other notable and potentially functional alterations to loci were observed within the class I region in an area shown to be important in susceptibility to psoriasis [28–30]: (1) The locus C6orf205 encoding a putative transmembrane protein [31,32] possesses a coding minisatellite in exon 2: PGF and COX both possess only 27 copies, whereas QBL possesses 31 copies of the 45-mer repeat sequence, thus extending the coding sequence (CDS) by 180 nucleotides and the translated CDS by 60 amino acids.