There has been accumulated evidence that AT1R blockade therapy suppresses tumour growth, metastasis and angiogenesis in experimental animal models (Rivera et al, 2001; Fujita et al, 2002; Miyajima et al, 2002; Egami et al, 2003; Uemura et al, 2003; Arrieta et al, 2005), and we also demonstrated that an AT1R blocker suppressed the peritoneal dissemination of ovarian cancer in a mouse model (Suganuma et al, 2005). The gene discussed is AGTR1; the disease is neoplasm.