High levels of EGFR was also found in the nuclei of many tumours, including those of skin, breast, bladder, cervix, adrenocorticord, thyroid and oral cavity (Kamio et al, 1990; Lipponen and Eskelinen, 1994; Lin et al, 2001; Marti et al, 2001; Lo et al, 2005a, 2005c; Psyrri et al, 2005). This evidence concerns the gene EGFR and neoplasm.