PTTG1 and neoplasm: As a result, the staining intensity of PTTG-1 expression (p = 0.047), tumor stage (p = 0,051), performance status (p = 0.015), LDH level (p = 0.001) and hemoglobin level (p= 0.011) were identified as independent prognostic parameters by the Cox regression modell (Table 3).