CD8A and familial pancreatic carcinoma: Furthermore, we previously demonstrated the prognostic significance of infiltrating CD8+ T cells in pancreatic cancer, gallbladder cancer, bile duct cancer and oesophageal squamous cell carcinoma (Cho et al, 2003; Nakakubo et al, 2003; Oshikiri et al, 2003; Fukunaga et al, 2004).