CD4 and cancer: To evaluate the possibility that a high level of both CD8+ and CD4+ T-cell infiltration in cancer stroma might correlate with favourable patient prognosis, the patients were classified into four groups: high-CD8+/high-CD4+ T cells (n=26), high-CD8+/low-CD4+ (n=27), low-CD8+/high-CD4+ (n=18) and low-CD8+/low-CD4+ T cells (n=38).