ANGPT2 and Sepsis: Serial measurements of Ang-2 revealed that the group of individuals with severe sepsis—the one that started with the highest circulating Ang-2—developed even higher peak Ang-2 during the course of hospitalization (32.4 ± 8.7 ng/ml), whereas hospitalized patients who did not have sepsis (controls) and patients who had sepsis but were without shock or multi-organ dysfunction (mild sepsis) had Ang-2 serum levels that generally remained ≤10 ng/ml.