TGFB1 and neoplasm: Although several groups demonstrated that increased TGFβ1 was associated with more aggressive tumour behavior and poorer survival (Gorsch et al, 1992; Dalal et al, 1993; Walker et al, 1994), other authors reported the absence of correlation between disease progression and TGFβ1 immunostaining or mRNA level (Dublin et al, 1993; Ghellal et al, 2000).