The multivariate model including age, sex, body -mass index, smoking, diabetes mellitus, arterial hypertension, hyperlipoproteinemia, family history of CHD, statins, log-transformed triglycerides, and apoB showed that patients with ACS and SM ≥48.1 mg/dl were at an elevated risk for further cardiovascular events (HR 1.8, 95%CI 1.0–3.3, p = 0.048, Table 4). The gene discussed is APOB; the disease is hyperlipoproteinemia.