Remarkably, results from a recent genomic profiling study on the impact of type 1 and 2 diabetes on the kidney [13] show that Man2a1 expression does not change significantly in streptozotocin treated mice, a model for type 1 diabetes, when animals do not present advanced mesangial matrix expansion nor albuminuria. This evidence concerns the gene MAN2A1 and type 1 diabetes mellitus.