These results differ from previous studies where anti-adhesion therapy with monoclonal antibodies to E- and L-selectin has been reported to increase the release of pro-inflammatory cytokines IL-6, IL-8, and TNFR-1 in a baboon model of sepsis [18]; however, this previous study differs from the current one in its protocol. This evidence concerns the gene TNFRSF1A and Sepsis.