For example, interleukin-1α (IL-1α) pretreatment of mice altered the melanoma cell (B16F1) arrest pattern from 32 μm beyond the sinusoidal inlet to larger terminal portal venules (TPV) observed by intravital videomicroscopy, suggesting increased adhesive interactions between endothelial and tumor cells following IL-1α stimulation [24]. Here, IL1A is linked to melanoma.