GJB2 and deafness: Recently, in the same DFNB1 locus, a 309-kb deletion implicating the GJB6 gene, del(GJB6-D13S1830), has been identified, and was found to be very common in non-syndromic hearing-impaired patients from Spain, France, Israel, the United Kingdom and Brazil, suggesting also a possible GJB2 / GJB6 digenic pattern of inheritance of deafness [6,7].