MTR and neoplasm: Analysing all 67 patients, tumours with the MTR wild-type genotype (2756AA) showed a median survival time of 16 months whereas tumours with an MTR variant genotype (2756AG/2756GG) showed a median survival time of 42 months (Figure 2) (P=0.0463 according to the Wilcoxon test; P=0.566 according to the log-rank test).