Because EGFR alterations are a common feature of many malignant tumors, including non-small-cell lung and colon cancers and malignant melanoma, among others, a variety of techniques have been designed to target the EGFR and its downstream agents, including antibodies, antisense RNAs, and a large number of small molecule inhibitors [7,8]. Here, EGFR is linked to malignant colon neoplasm.