The induction of IIGP1 (Figure 1A), and other p47 GTPases (Figure S3), correlated with IFN-γ-induced growth inhibition of T. gondii. In untreated cells 24 h after infection, the frequency of PVs relative to total cells dropped to 58% of the 2-h value, probably reflecting astrocyte replication, while in the IFN-γ-treated cells the frequency of PVs dropped sharply over 24 h to only 17% of the 2-h value (Figure 1B). Here, IFNG is linked to infection.