RPS6KB1 and breast carcinoma: We have found 40 (44.9%) breast cancer tissues revealed moderate to high levels of mTOR(S2448) phosphorylation, whereas 64 (71.9%) and 52 (58.5%) out of 89 invasive breast carcinoma gave rise to positive staining (scores 2 and 3) on phosphorylated p70S6K(T389) and S6(S235/236), respectively (Table 2).