NFKB1 and Familial prostate cancer: Furthermore, emerging data obtained from human studies also suggest a potential role of NF-κB in prostate cancer tumorigenesis and/or in its behaviour in a clinical setting (Suh et al, 2002; Lessard et al, 2003; Fradet et al, 2004; Ismail et al, 2004; Ross et al, 2004).