In addition, these differences were evident when individuals were categorized according to the presence or absence of these genotypes: 56.5% of patients with RA were homozygous or heterozygous with respect to FCGR3A-158V, as compared with 11.1% of healthy individuals; and 43.5% of patients with RA were homozygous with respect to FCGR3A-158F, as compared with 88.9% of healthy individuals (χ2 = 5.42 with one degree of freedom; P < 0.02; Tables 1 and 2). The gene discussed is FCGR3A; the disease is rheumatoid arthritis.