ABCC8 and pancreatic insulinoma: The partial DNA sequence of canine SUR1 obtained from these insulinomas is homologous to a region that spans exons 7 and 8 of human SUR1 which codes for the c-terminal end of the linker region between the 7th and 8th transmembrane regions as well as a portion of the 8th transmembrane domain of the SUR1 protein.