EIF3A and breast cancer: DNA vaccination with plasmids coding for the transmembrane and extracellular domains of the rat p185 (EC-TM plasmids) elicits a protective immune response against spontaneously arising mammary tumours in BALB/c mice transgenic for the gene encoding the mutated form of the rat p185 (Rovero et al, 2000; Di Carlo et al, 2001; Dela Cruz et al, 2003; Quaglino et al, 2004a).